Articles

Publications related to ongoing projects

Prével C., Pellerano M., Gonzalez Vera JA, Henri P., Meunier L., Vollaire J., Josserand V. & Morris M.C. Monitoring CDK4 activity in cell extracts, melanoma xenografts and skin biopsies with a peptide biosensor, Biosensors & Bioelectronics, 2016 Apr 22 ;85:371-380. doi : 10.1016/j.bios.2016.04.050. (2016)

Morgan Pellerano, Delphine Naud-Martin, Marie-Paule Teulade-Fichou, Florence Mahuteau-Betzer & Morris M.C. TP2-Rho is a Sensitive Solvatochromic Red-shifted Probe for Monitoring the Interactions between CDK4 and Cyclin D.  Chembiochem. 2016 Apr 15;17(8):737-44. doi: 10.1002/cbic.201500641. Epub 2016 Mar 17.PMID: 26946188. (2016)

González-Vera JA, Fueyo-González F, Alkorta I, Peyressatre M, Morris MC, Herranz R (2016) Highly solvatochromic and tunable fluorophores based on a 4,5-quinolimide scaffold: novel CDK5 probes. Chem Commun 52, 9652-9655. (2016)

Peyressatre M., Prével C., Pellerano M., Morris M.C. Targeting Cyclin-Dependent Kinases in Human Cancers : from small molecules to peptide inhibitors. Cancers 23 ;7(1):179-237. (2015)

Floquet N, Costa MG, Batista PR, Renault P, Bisch PM, Raussin F, Martinez J, Morris MC, Perahia D. Conformational Equilibrium of CDK/Cyclin Complexes by Molecular Dynamics with Excited Normal Modes. Biophys J. 109(6):1179-89. doi: 10.1016/j.bpj.2015.07.003. (2015)

Tîlmaciu CM & Morris M.C.  Carbon Nanotube Biosensors , Frontiers Chemical Biology, Front. Chem., 3 (59), 1-21 http://dx.doi.org/10.3389/fchem.2015.00059. (2015)

Gonzalez-Vera JA & Morris M.C. Fluorescent Biosensors for probing the Dynamic Behaviour of Protein Kinases , Proteomes, 3, 369-410; doi:10.3390/proteomes3040369. (2015)

Prével C., Kurzawa L., Van T.N.N. & Morris MC. Fluorescent biosensors for drug discovery- New tools for Old Targets – Screening for Inhibitors of Cyclin-dependent kinases. European Journal of Medicinal Chemistry. 10.1016/j.ejmech.2014.10.003. (2014)

Van T.N.N., Pellerano, M., Lykaso S., Morris, M.C. Fluorescent protein biosensor for probing CDK/Cyclin activity in vitro and in living cells. ChembioChem 15 (15) : 2298–2305. (2014)

Morris MC. Spotlight on Fluorescent Biosensors—Tools for Diagnostics and Drug Discovery. ACS Chem.Med.Lett.,  5, 99-101 DOI: 10.1021/ml400472e. (2014)

Prével, C., Pellerano, M., Van, T.N.N., Morris, M.C. (2014).  Fluorescent Biosensors for High Throughput Screening of Protein Kinase Inhibitors. Biotechnology J. 9, 253-65. (2014)

Van TNN., Pellerano M., LyKaSo S. & Morris MC. Fluorescent biosensor for probing CDK/Cyclin kinase activity in vitro and in living cells, ChemBioChem. 15 (15) 2298-2305. (2014)

Fluorescent Biosensors (2014) Biotechnology Journal, Wiley press, Editors: M.C.Morris & M.Blondel. (2014)

Fluorescence-Based Biosensors – concepts and applications Progress in Molecular Biology and Translational Science, Elsevier press, ISBN: 978-0-12-386932-6, Editor M.C.Morris, 113, 1-414 (2013)

Morris MC. Fluorescent Biosensors – Probing Protein Kinase Function in Cancer and Drug Discovery. Biochim Biophys Acta 1834(7),1387-95. (2013)

Van, T.N.N. & Morris, M.C. Fluorescent sensors of protein kinases : from basics to biomedical applications.Progr. Mol. Biol. Trans. Science, 113, 217-274. (2013)

Morris, M.C. Fluorescent Biosensors for Cancer Cell Imaging and Diagnostics. Biosensors and Cancer , CRC press, Editor V.Preedy and J.Hunter, ISBN 978-1-57808-734-1. (2012)

Kurzawa L, Pellerano M, Coppolani JB, Morris MC.Fluorescent peptide bioprobe for quantification of cyclin-dependent kinases in living cells, PloS ONE, 6(10):e26555. (2011)

Kurzawa L & Morris MC. Cell Cycle Markers and Biosensors, ChemBioChem, 11 (8), 1037-1047. (2010)

Kurzawa L, Pellerano M. & Morris MC. PEP- and CADY-mediated Delivery of Fluorescent Peptides and Proteins into Living Cells, Biochimica et Biophysica Acta, 1798, 2274-2285. (2010)

Morris M.C. Fluorescent Biosensors of Intracellular Targets : from genetically-encoded reporters to modular polypeptide probes. Cell Biochem.Biophys. 56,19-37(2010)

Gondeau, C., Chaloin-Gerbal, S., Bello, P., Aldrian-Herrada, G., Morris M.C. & Divita G. Design of a novel class of peptide inhibitors of cyclin-dependent kinase/cyclin activation. The Journal of Biological Chemistry, 280 (14): 13793-13800. (2005)

Morris, M.C., Gondeau, C., Tainer, J.A. & Divita, G. Kinetic mechanism of activation of the cdk2/cyclin A complex : key role of the C-lobe of the cdk. The Journal of Biological Chemistry, 277, 23847-23853.(2002)

Morris, M.C., Heitz, F. & Divita, G. Molecular mechanism of formation of cdk-cyclin complexes: role in cell cycle progression. Recent Research Developments in Biochemistry, 1, 117-132. (1999)

Morris, M.C., Heitz, F., Fesquet, D., Cavadore, J.-C., Dorée,M. & Divita, G. Interactions of cyclins with cyclin-dependent kinases: a common interactive mechanism. Biochemistry, 36, 4995-5003. (1997)